In this Issue:
Colorectal cancer
Intensive follow-up improves survival
Multiple mechanisms of EGFRbbresistance
Metastatic colorectal cancer
Resistance mechanisms can co-exist
Mismatch-repair status predicts benefit of PD-1 blockade
BEAMing provides non-invasive analysis of tumours
Capecitabine + bevacizumab maintenance delays progression
TAS-102 prolongs survival in refractory disease
Rectal cancer
Similar outcomes with laparoscopic vs open surgery
Watchful waiting rather than surgery for distal tumours
No survival benefit with adjuvant chemotherapy
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